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Uncovering the source of mitochondrial superoxide in pro-inflammatory macrophages: Insights from immunometabolism
Mitochondrial-derived reactive oxygen species are important as antimicrobial agents and redox signals in pro-inflammatory macrophages. Macrophages produce superoxide in response to the TLR4 ligand LPS. However, the mechanism of LPS-induced superoxide generation is not fully understood. Superoxide is...
Autores principales: | Casey, Alva M., Murphy, Michael P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614207/ https://www.ncbi.nlm.nih.gov/pubmed/35792320 http://dx.doi.org/10.1016/j.bbadis.2022.166481 |
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