Gaucher disease protects against tuberculosis

Biallelic mutations in the glucocerebrosidase (GBA1) gene cause Gaucher disease, characterized by lysosomal accumulation of glucosylceramide and glucosylsphingosine in macrophages. Gaucher and other lysosomal diseases occur with high frequency in Ashkenazi Jews. It has been proposed that the underly...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Jingwen, Hale, Victoria L., Lelieveld, Lindsey T., Whitworth, Laura J., Busch-Nentwich, Elisabeth M., Troll, Mark, Edelstein, Paul H., Cox, Timothy M., Roca, Francisco J., Aerts, Johannes M. F. G., Ramakrishnan, Lalita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614233/
https://www.ncbi.nlm.nih.gov/pubmed/36745788
http://dx.doi.org/10.1073/pnas.2217673120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614233/
https://www.ncbi.nlm.nih.gov/pubmed/36745788
http://dx.doi.org/10.1073/pnas.2217673120

Ejemplares similares