Cargando…
Single-cell fate mapping reveals widespread clonal ignorance of low-affinity T cells exposed to systemic infection
T cell ignorance is a specific form of immunological tolerance. It describes the maintenance of naivety in antigen-specific T cells in vivo despite the presence of their target antigen. It is thought to mainly play a role during the steady state, when self-antigens are presented in absence of costim...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614329/ https://www.ncbi.nlm.nih.gov/pubmed/36458456 http://dx.doi.org/10.1002/eji.202250009 |