Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells

DNA damage response (DDR) during interphase involves active signaling and repair to ensure genomic stability. However, how mitotic cells respond to DNA damage remains poorly understood. Supported by correlative live-/fixed-cell microscopy, it was found that mitotic cells exposed to several cancer ch...

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Detalles Bibliográficos
Autores principales: Novais-Cruz, Marco, Pombinho, António, Sousa, Mafalda, Maia, André F., Maiato, Helder, Ferrás, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614429/
https://www.ncbi.nlm.nih.gov/pubmed/36989031
http://dx.doi.org/10.1091/mbc.E22-11-0518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614429/
https://www.ncbi.nlm.nih.gov/pubmed/36989031
http://dx.doi.org/10.1091/mbc.E22-11-0518

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