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Mitotic DNA damage promotes chromokinesin-mediated missegregation of polar chromosomes in cancer cells
DNA damage response (DDR) during interphase involves active signaling and repair to ensure genomic stability. However, how mitotic cells respond to DNA damage remains poorly understood. Supported by correlative live-/fixed-cell microscopy, it was found that mitotic cells exposed to several cancer ch...
Autores principales: | Novais-Cruz, Marco, Pombinho, António, Sousa, Mafalda, Maia, André F., Maiato, Helder, Ferrás, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614429/ https://www.ncbi.nlm.nih.gov/pubmed/36989031 http://dx.doi.org/10.1091/mbc.E22-11-0518 |
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