NRF2 Activation Reprograms Defects in Oxidative Metabolism to Restore Macrophage Function in Chronic Obstructive Pulmonary Disease

RATIONALE: Chronic obstructive pulmonary disease (COPD) is a disease characterized by persistent airway inflammation and disordered macrophage function. The extent to which alterations in macrophage bioenergetics contribute to impaired antioxidant responses and disease pathogenesis has yet to be ful...

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Detalles Bibliográficos
Autores principales: Ryan, Eilise M., Sadiku, Pranvera, Coelho, Patricia, Watts, Emily R., Zhang, Ailiang, Howden, Andrew J. M., Sanchez-Garcia, Manuel A., Bewley, Martin, Cole, Joby, McHugh, Brian J., Vermaelen, Wesley, Ghesquiere, Bart, Carmeliet, Peter, Rodriguez Blanco, Giovanny, Von Kriegsheim, Alex, Sanchez, Yolanda, Rumsey, William, Callahan, James F., Cooper, George, Parkinson, Nicholas, Baillie, Kenneth, Cantrell, Doreen A., McCafferty, John, Choudhury, Gourab, Singh, Dave, Dockrell, David H., Whyte, Moira K. B., Walmsley, Sarah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614437/
https://www.ncbi.nlm.nih.gov/pubmed/36724365
http://dx.doi.org/10.1164/rccm.202203-0482OC

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614437/
https://www.ncbi.nlm.nih.gov/pubmed/36724365
http://dx.doi.org/10.1164/rccm.202203-0482OC

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