Cargando…
Emerging mechanisms of telomerase reactivation in cancer
Mutations in the promoter of human telomerase reverse transcriptase (hTERT) result in hyperactivation of hTERT. Notably, all mutations are G>A transitions, frequently found in a wide range of cancer types, and causally associated with cancer progression. Initially, the mutations were understood t...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614490/ https://www.ncbi.nlm.nih.gov/pubmed/35568649 http://dx.doi.org/10.1016/j.trecan.2022.03.005 |