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DNA topoisomerases: Advances in understanding of cellular roles and multi-protein complexes via structure-function analysis

DNA topoisomerases, capable of manipulating DNA topology, are ubiquitous and indispensable for cellular survival due to the numerous roles they play during DNA metabolism. As we review here, current structural approaches have revealed unprecedented insights into the complex DNA-topoisomerase interac...

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Detalles Bibliográficos
Autores principales: McKie, Shannon J., Neuman, Keir C., Maxwell, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614492/
https://www.ncbi.nlm.nih.gov/pubmed/33480441
http://dx.doi.org/10.1002/bies.202000286