A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins

Saposins are lipid transfer proteins required for the degradation of sphingolipids in the lysosome. These small proteins bind lipids by transitioning from a closed, monomeric state to an open conformation exposing a hydrophobic surface that binds and shields hydrophobic lipid tails from the aqueous...

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Detalles Bibliográficos
Autores principales: Shamin, Maria, Spratley, Samantha J., Graham  , Stephen C., Deane , Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614494/
https://www.ncbi.nlm.nih.gov/pubmed/37143956
http://dx.doi.org/10.1177/25152564211052382

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614494/
https://www.ncbi.nlm.nih.gov/pubmed/37143956
http://dx.doi.org/10.1177/25152564211052382

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