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A Tetrameric Assembly of Saposin A: Increasing Structural Diversity in Lipid Transfer Proteins
Saposins are lipid transfer proteins required for the degradation of sphingolipids in the lysosome. These small proteins bind lipids by transitioning from a closed, monomeric state to an open conformation exposing a hydrophobic surface that binds and shields hydrophobic lipid tails from the aqueous...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614494/ https://www.ncbi.nlm.nih.gov/pubmed/37143956 http://dx.doi.org/10.1177/25152564211052382 |