Competition for refuelling rather than cyclic re-entry initiation evident in germinal centers

Antibody affinity maturation occurs in germinal centers (GCs) through iterative rounds of somatic hypermutation and proliferation in dark zones (DZs) and selection in light zones (LZs). GC B cells exit cell cycle a number of hours before entering LZs, therefore continued participation in responses r...

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Detalles Bibliográficos
Autores principales: Long, Ziqi, Phillips, Bethan, Radtke, Daniel, Meyer-Hermann, Michael, Bannard, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614495/
https://www.ncbi.nlm.nih.gov/pubmed/35275753
http://dx.doi.org/10.1126/sciimmunol.abm0775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614495/
https://www.ncbi.nlm.nih.gov/pubmed/35275753
http://dx.doi.org/10.1126/sciimmunol.abm0775

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