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Human platelets release amyloid peptides β(1-40) and β(1-42) in response to hemostatic, immune, and hypoxic stimuli

BACKGROUND: Platelets contain high levels of amyloid β (Aβ) peptides and have been suggested to participate in the deposition of amyloid plaques in Alzheimer’s disease. OBJECTIVES: This study aimed to determine whether human platelets release pathogenic Aβ peptides Aβ(1-42) and Aβ(1-40) and to chara...

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Detalles Bibliográficos
Autores principales: Wolska, Nina, Celikag, Meral, Failla, Antonio Virgilio, Tarafdar, Anuradha, Renné, Thomas, Torti, Mauro, Canobbio, Ilaria, Pula, Giordano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614566/
https://www.ncbi.nlm.nih.gov/pubmed/37222974
http://dx.doi.org/10.1016/j.rpth.2023.100154