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CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythaemia
The process of platelet production has so far been understood to be a two-stage process: megakaryocyte (MK) maturation from haematopoietic stem cells followed by proplatelet formation, with each phase regulating the peripheral blood platelet count. Proplatelet formation releases “beads-on-a-string”...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614665/ https://www.ncbi.nlm.nih.gov/pubmed/35051265 http://dx.doi.org/10.1182/blood.2021013113 |