CRLF3 plays a key role in the final stage of platelet genesis and is a potential therapeutic target for thrombocythaemia

The process of platelet production has so far been understood to be a two-stage process: megakaryocyte (MK) maturation from haematopoietic stem cells followed by proplatelet formation, with each phase regulating the peripheral blood platelet count. Proplatelet formation releases “beads-on-a-string”...

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Detalles Bibliográficos
Autores principales: Bennett, Cavan, Lawrence, Moyra, Guerrero, Jose A., Stritt, Simon, Waller, Amie K., Yan, Yahui, Mifsud, Richard W., Ballester-Beltran, Jose, Baig, Ayesha, Mueller, Annett, Mayer, Louisa, Warland, James, Penkett, Christopher J., Akbari, Parsa, Moreau, Thomas, Evans, Amanda L., Mookerjee, Souradip, Hoffman, Gary J., Saeb-Parsy, Kourosh, Adams, David J., Couzens, Amber L., Bender, Markus, Erber, Wendy N., Nieswandt, Bernhard, Read, Randy J., Ghevaert, Cedric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614665/
https://www.ncbi.nlm.nih.gov/pubmed/35051265
http://dx.doi.org/10.1182/blood.2021013113

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