Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages

5-methoxy tryptophan (5-MTP) is an anti-fibrotic metabolite made by fibroblasts and epithelial cells, present in a micromolar concentrations in human blood, and is associated with the progression of fibrotic kidney disease, but the mechanism is unclear. Here, we show by microscopy and functional ass...

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Detalles Bibliográficos
Autores principales: Maassen, Sjors, Warner, Harry, Ioannidis, Melina, Jansma, Jack, Markus, Hugo, El Aidy, Sahar, Chiara, María-Dolores, Chiara, Jose Luis, Maierhofer, Larissa, Weavers, Helen, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614693/
https://www.ncbi.nlm.nih.gov/pubmed/35753585
http://dx.doi.org/10.1016/j.freeradbiomed.2022.06.235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614693/
https://www.ncbi.nlm.nih.gov/pubmed/35753585
http://dx.doi.org/10.1016/j.freeradbiomed.2022.06.235

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