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Acetylcholine boosts dendritic NMDA spikes in a CA3 pyramidal neuron model
Acetylcholine has been proposed to facilitate the formation of memory ensembles within the hippocampal CA3 network, by enhancing plasticity at CA3-CA3 recurrent synapses. Regenerative NMDA receptor (NMDAR) activation in CA3 neuron dendrites (NMDA spikes) increase synaptic Ca(2+) influx and can trigg...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614718/ https://www.ncbi.nlm.nih.gov/pubmed/34780920 http://dx.doi.org/10.1016/j.neuroscience.2021.11.014 |