Ectocytosis renders T cell receptor signaling self-limiting at the immune synapse

Cytotoxic T lymphocytes (CTLs) kill virus-infected and cancer cells via T cell receptor (TCR) recognition. How CTLs terminate signaling and disengage to allow serial killing has remained a mystery. TCR activation triggers membrane specialization within the immune synapse including the production of...

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Detalles Bibliográficos
Autores principales: Stinchcombe, Jane C., Asano, Yukako, Kaufman, Christopher J.G., Bohlig, Kristin, Peddie, Christopher J., Collinson, Lucy M., Nadler, André, Griffiths, Gillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614748/
https://www.ncbi.nlm.nih.gov/pubmed/37228189
http://dx.doi.org/10.1126/science.abp8933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614748/
https://www.ncbi.nlm.nih.gov/pubmed/37228189
http://dx.doi.org/10.1126/science.abp8933

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