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Early phase clinical trials in oncology: realising the potential of seamless designs

BACKGROUND: The pharmaceutical industry’s productivity has been declining over the last two decades and high attrition rates and reduced regulatory approvals are being seen. The development of oncology drugs is particularly challenging with low rates of approval for novel treatments when compared wi...

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Detalles Bibliográficos
Autores principales: Jaki, Thomas, Burdon, Abigail, Chen, Xijin, Mozgunov, Pavel, Zheng, Haiyan, Baird, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614750/
https://www.ncbi.nlm.nih.gov/pubmed/37301716
http://dx.doi.org/10.1016/j.ejca.2023.05.005