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Early phase clinical trials in oncology: realising the potential of seamless designs
BACKGROUND: The pharmaceutical industry’s productivity has been declining over the last two decades and high attrition rates and reduced regulatory approvals are being seen. The development of oncology drugs is particularly challenging with low rates of approval for novel treatments when compared wi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614750/ https://www.ncbi.nlm.nih.gov/pubmed/37301716 http://dx.doi.org/10.1016/j.ejca.2023.05.005 |