Cargando…

Continuous synthesis of E. coli genome sections and Mb-scale human DNA assembly

Whole-genome synthesis provides a powerful approach for understanding and expanding organism function(1–3). To build large genomes rapidly, scalably, and in parallel we need: (1) methods for assembling megabases of DNA from shorter pre-cursors; and (2) strategies for rapidly and scalably replacing t...

Descripción completa

Detalles Bibliográficos
Autores principales: Zürcher, Jérôme F., Kleefeldt, Askar A., Funke, Louise F. H., Birnbaum, Jakob, Fredens, Julius, Grazioli, Simona, Liu, Kim C., Spinck, Martin, Petris, Gianluca, Murat, Pierre, Rehm, Fabian B. H., Sale, Julian E., Chin, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614783/
https://www.ncbi.nlm.nih.gov/pubmed/37380776
http://dx.doi.org/10.1038/s41586-023-06268-1