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The angiopoietin receptor Tie2 is atheroprotective in arterial endothelium

Leukocytes and resident cells in the arterial wall contribute to atherosclerosis, especially at sites of disturbed blood flow. Expression of endothelial Tie1 receptor tyrosine kinase is enhanced at these sites, and attenuation of its expression reduces atherosclerotic burden and decreases inflammati...

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Detalles Bibliográficos
Autores principales: Anisimov, Andrey, Fang, Shentong, Hemanthakumar, Karthik Amudhala, Örd, Tiit, van Avondt, Kristof, Chevre, Raphael, Toropainen, Anu, Singha, Prosanta, Gilani, Huda, Nguyen, Su D., Karaman, Sinem, Korhonen, Emilia A., Adams, Ralf H., Augustin, Hellmut G., Öörni, Katariina, Soehnlein, Oliver, Kaikkonen, Minna U., Alitalo, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614785/
https://www.ncbi.nlm.nih.gov/pubmed/37476204
http://dx.doi.org/10.1038/s44161-023-00224-y