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3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression
Formation of the 3′end of a eukaryotic mRNA is a key step in the production of a mature transcript. This process is mediated by a number of protein factors that cleave the pre-mRNA, add a poly(A) tail, and regulate transcription by protein dephosphorylation. Cleavage and polyadenylation specificity...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614891/ https://www.ncbi.nlm.nih.gov/pubmed/37001138 http://dx.doi.org/10.1146/annurev-biochem-052521-012445 |