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3′-End Processing of Eukaryotic mRNA: Machinery, Regulation, and Impact on Gene Expression

Formation of the 3′end of a eukaryotic mRNA is a key step in the production of a mature transcript. This process is mediated by a number of protein factors that cleave the pre-mRNA, add a poly(A) tail, and regulate transcription by protein dephosphorylation. Cleavage and polyadenylation specificity...

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Detalles Bibliográficos
Autores principales: Boreikaitė, Vytautė, Passmore, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614891/
https://www.ncbi.nlm.nih.gov/pubmed/37001138
http://dx.doi.org/10.1146/annurev-biochem-052521-012445

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