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Excitability properties of mouse and human skeletal muscle fibres compared by muscle velocity recovery cycles

Mouse models of skeletal muscle channelopathies are not phenocopies of human disease. In some cases (e.g., Myotonia Congenita) the phenotype is much more severe, whilst in others (e.g. Hypokalaemic periodic paralysis) rodent physiology is protective. This suggests a species’ difference in muscle exc...

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Detalles Bibliográficos
Autores principales: Suetterlin, K. J., Männikkö, R., Matthews, E., Greensmith, L., Hanna, M.G., Bostock, H., Tan, S.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614892/
https://www.ncbi.nlm.nih.gov/pubmed/35339342
http://dx.doi.org/10.1016/j.nmd.2022.02.011