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YAP/TAZ as master regulators in cancer – modulation, function and therapeutic approaches

Our understanding of the function of the transcriptional regulators YAP/TAZ in cancer is advancing. In this Review, we provide an update on recent progress in YAP/TAZ biology, their regulation by Hippo signaling and mechanotransduction, and highlight open questions. YAP/TAZ signaling is an addiction...

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Detalles Bibliográficos
Autores principales: Piccolo, Stefano, Panciera, Tito, Contessotto, Paolo, Cordenonsi, Michelangelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614914/
https://www.ncbi.nlm.nih.gov/pubmed/36564601
http://dx.doi.org/10.1038/s43018-022-00473-z