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Children With Noncritical Infections Have Increased Intestinal Permeability, Endotoxemia and Altered Innate Immune Responses

BACKGROUND: Children with critical illness have increased intestinal permeability and a period of immunoparalysis, mediated by elevated circulating endotoxin. Whether children with less severe infections have similar changes is uncertain. METHODS: We conducted a proof-of-concept pilot study, enrolli...

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Detalles Bibliográficos
Autores principales: Sturgeon, Jonathan P., Bourke, Claire D., Prendergast, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7614937/
https://www.ncbi.nlm.nih.gov/pubmed/30985520
http://dx.doi.org/10.1097/INF.0000000000002311