Vaccination with Plasmodium vivax Duffy-binding protein inhibits parasite growth during controlled human malaria infection

There are no licensed vaccines against Plasmodium vivax. We conducted two Phase I/IIa clinical trials to assess two vaccines targeting P. vivax Duffy-binding protein region II (PvDBPII). Recombinant viral vaccines using chimpanzee adenovirus 63 (ChAd63) and modified vaccinia virus Ankara (MVA) vecto...

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Detalles Bibliográficos
Autores principales: Hou, Mimi M., Barrett, Jordan R., Themistocleous, Yrene, Rawlinson, Thomas A., Diouf, Ababacar, Martinez, Francisco J., Nielsen, Carolyn M., Lias, Amelia M., King, Lloyd D. W., Edwards, Nick J., Greenwood, Nicola M., Kingham, Lucy, Poulton, Ian D., Khozoee, Baktash, Goh, Cyndi, Hodgson, Susanne H., Lochlainn, Dylan J. Mac, Salkeld, Jo, Guillotte-Blisnick, Micheline, Huon, Christèle, Mohring, Franziska, Reimer, Jenny M., Chauhan, Virander S., Mukherjee, Paushali, Biswas, Sumi, Taylor, Iona J., Lawrie, Alison M., Cho, Jee-Sun, Nugent, Fay L., Long, Carole A., Moon, Robert W., Miura, Kazutoyo, Silk, Sarah E., Chitnis, Chetan E., Minassian, Angela M., Draper, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615121/
https://www.ncbi.nlm.nih.gov/pubmed/37437014
http://dx.doi.org/10.1126/scitranslmed.adf1782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615121/
https://www.ncbi.nlm.nih.gov/pubmed/37437014
http://dx.doi.org/10.1126/scitranslmed.adf1782

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