Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease

Murine intraepithelial γδ T cells include unique, tissue-protective cells selected by epithelial Butyrophilin-like (BTNL) heteromers. Interrogating whether this biology is conserved in humans, we characterized the colonic γδ T cell compartment, identifying a diverse repertoire that includes a phenot...

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Detalles Bibliográficos
Autores principales: Dart, Robin J, Zlatareva, Iva, Vantourout, Pierre, Theodoridis, Efstathios, Amar, Ariella, Kannambath, Shichina, East, Philip, Recaldin, Timothy, Mansfield, John C, Lamb, Christopher A, Parkes, Miles, Irving, Peter M, Prescott, Natalie J, Hayday, Adrian C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615126/
https://www.ncbi.nlm.nih.gov/pubmed/37708268
http://dx.doi.org/10.1126/science.adh0301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615126/
https://www.ncbi.nlm.nih.gov/pubmed/37708268
http://dx.doi.org/10.1126/science.adh0301

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