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Conserved γδ T cell selection by BTNL proteins limits progression of human inflammatory bowel disease
Murine intraepithelial γδ T cells include unique, tissue-protective cells selected by epithelial Butyrophilin-like (BTNL) heteromers. Interrogating whether this biology is conserved in humans, we characterized the colonic γδ T cell compartment, identifying a diverse repertoire that includes a phenot...
Autores principales: | Dart, Robin J, Zlatareva, Iva, Vantourout, Pierre, Theodoridis, Efstathios, Amar, Ariella, Kannambath, Shichina, East, Philip, Recaldin, Timothy, Mansfield, John C, Lamb, Christopher A, Parkes, Miles, Irving, Peter M, Prescott, Natalie J, Hayday, Adrian C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615126/ https://www.ncbi.nlm.nih.gov/pubmed/37708268 http://dx.doi.org/10.1126/science.adh0301 |
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