ADAMTS-7 modulates atherosclerotic plaque formation by degradation of TIMP-1

BACKGROUND: The ADAMTS7 locus was genome-wide significantly associated with coronary artery disease (CAD). Lack of the extracellular matrix (ECM) protease ADAMTS-7 was shown to reduce atherosclerotic plaque formation. Here, we sought to identify molecular mechanisms and downstream targets of ADAMTS-...

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Detalles Bibliográficos
Autores principales: Sharifi, M. Amin, Wierer, Michael, Dang, Tan An, Milic, Jelena, Moggio, Aldo, Sachs, Nadja, von Scheidt, Moritz, Hinterdobler, Julia, Müller, Philipp, Werner, Julia, Stiller, Barbara, Aherrahrou, Zouhair, Erdmann, Jeanette, Zaliani, Andrea, Graettinger, Mira, Reinshagen, Jeanette, Gul, Sheraz, Gribbon, Philip, Maegdefessel, Lars, Bernhagen, Jürgen, Sager, Hendrik B., Mann, Matthias, Schunkert, Heribert, Kessler, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615141/
https://www.ncbi.nlm.nih.gov/pubmed/37675562
http://dx.doi.org/10.1161/CIRCRESAHA.123.322737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615141/
https://www.ncbi.nlm.nih.gov/pubmed/37675562
http://dx.doi.org/10.1161/CIRCRESAHA.123.322737

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