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Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles
Poor understanding of intracellular delivery and targeting hinders development of nucleic acid-based therapeutics transported by nanoparticles. Utilizing a siRNA-targeting and small molecule profiling approach with advanced imaging and machine learning biological insights is generated into the mecha...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615154/ https://www.ncbi.nlm.nih.gov/pubmed/37317010 http://dx.doi.org/10.1002/smtd.202201695 |