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Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles

Poor understanding of intracellular delivery and targeting hinders development of nucleic acid-based therapeutics transported by nanoparticles. Utilizing a siRNA-targeting and small molecule profiling approach with advanced imaging and machine learning biological insights is generated into the mecha...

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Detalles Bibliográficos
Autores principales:	Hunter, Morag Rose, Cui, Lili, Porebski, Benjamin Thomas, Pereira, Sara, Sonzini, Silvia, Odunze, Uchechukwu, Iyer, Preeti, Engkvist, Ola, Lloyd, Rebecca Louise, Peel, Samantha, Sabirsh, Alan, Ross-Thriepland, Douglas, Jones, Arwyn Tomos, Desai, Arpan Shailesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615154/ https://www.ncbi.nlm.nih.gov/pubmed/37317010 http://dx.doi.org/10.1002/smtd.202201695

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