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Nodal signaling establishes a competency window for stochastic cell fate switching
Specification of the germ layers by Nodal signaling has long been regarded as an archetype of how graded morphogens induce different cell fates. However, this deterministic model cannot explain why only a subset of cells at the early zebrafish embryo margin adopt the endodermal fate, whereas their i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615190/ https://www.ncbi.nlm.nih.gov/pubmed/36473458 http://dx.doi.org/10.1016/j.devcel.2022.11.008 |