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PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection
Disruption of cellular activities by pathogen virulence factors can trigger innate immune responses. Interferon-gamma (IFNγ)-inducible antimicrobial factors, such as the guanylate binding proteins (GBPs), promote cell-intrinsic defense by attacking intracellular pathogens and by inducing programmed...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615196/ https://www.ncbi.nlm.nih.gov/pubmed/37797010 http://dx.doi.org/10.1126/science.adg2253 |