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The -KTS splice variant of WT1 is essential for ovarian determination in mice

Sex determination in mammals depends on the differentiation of the supporting lineage of the gonads into Sertoli or pre-granulosa cells that govern testis and ovary development, respectively. While the Y-linked testis-determining gene Sry has been identified, the ovarian-determining factor remains u...

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Detalles Bibliográficos
Autores principales: Gregoire, Elodie P, De Cian, Marie-Cécile, Migale, Roberta, Perea-Gomez, Aitana, Schaub, Sébastien, Bellido-Carreras, Natividad, Stévant, Isabelle, Mayère, Chloé, Neirijnck, Yasmine, Loubat, Agnès, Rivaud, Paul, Sopena, Miriam Llorian, Lachambre, Simon, Linssen, Margot M., Hohenstein, Peter, Lovell-Badge, Robin, Nef, Serge, Chalmel, Frédéric, Schedl, Andreas, Chaboissier, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615308/
https://www.ncbi.nlm.nih.gov/pubmed/37917714
http://dx.doi.org/10.1126/science.add8831