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Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir
Positron emission tomography (PET) imaging allows monitoring the progression of amyloid aggregation in the living brain. [(18)F]-Flortaucipir is the only approved PET tracer compound for the visualisation of tau aggregation. Here, we describe cryo-EM experiments on tau filaments in the presence and...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615338/ https://www.ncbi.nlm.nih.gov/pubmed/37330290 http://dx.doi.org/10.1016/j.jmb.2023.168025 |