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Cryo-EM Structures of Chronic Traumatic Encephalopathy Tau Filaments with PET Ligand Flortaucipir

Positron emission tomography (PET) imaging allows monitoring the progression of amyloid aggregation in the living brain. [(18)F]-Flortaucipir is the only approved PET tracer compound for the visualisation of tau aggregation. Here, we describe cryo-EM experiments on tau filaments in the presence and...

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Detalles Bibliográficos
Autores principales:	Shi, Yang, Ghetti, Bernardino, Goedert, Michel, Scheres, Sjors H. W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615338/ https://www.ncbi.nlm.nih.gov/pubmed/37330290 http://dx.doi.org/10.1016/j.jmb.2023.168025

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