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Using biomarkers to allocate patients in a response-adaptive clinical trial
In this paper, we discuss a response adaptive randomization method, and why it should be used in clinical trials for rare diseases compared to a randomized controlled trial with equal fixed randomization. The developed method uses a patient’s biomarkers to alter the allocation probability to each tr...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615340/ https://www.ncbi.nlm.nih.gov/pubmed/38045870 http://dx.doi.org/10.1080/03610918.2021.2004420 |