Cargando…
Using biomarkers to allocate patients in a response-adaptive clinical trial
In this paper, we discuss a response adaptive randomization method, and why it should be used in clinical trials for rare diseases compared to a randomized controlled trial with equal fixed randomization. The developed method uses a patient’s biomarkers to alter the allocation probability to each tr...
Autores principales: | Jackson, H., Bowen, S., Jaki, T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615340/ https://www.ncbi.nlm.nih.gov/pubmed/38045870 http://dx.doi.org/10.1080/03610918.2021.2004420 |
Ejemplares similares
-
A novel statistical test for treatment differences in clinical trials using a response-adaptive forward-looking Gittins Index Rule
por: Barnett, Helen Yvette, et al.
Publicado: (2021) -
A Bayesian adaptive design for clinical trials in rare diseases
por: Williamson, S. Faye, et al.
Publicado: (2017) -
Response adaptive intervention allocation in stepped‐wedge cluster randomized trials
por: Grayling, Michael J., et al.
Publicado: (2022) -
Improving safety of the continual reassessment method via a modified allocation rule
por: Mozgunov, Pavel, et al.
Publicado: (2019) -
Adaptive treatment allocation and selection in multi-arm clinical trials: a Bayesian perspective
por: Arjas, Elja, et al.
Publicado: (2022)