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Radiosensitizing effects of c-myc gene knockdown-induced G2/M phase arrest by intrinsic stimuli via the mitochondrial signaling pathway

Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and its long-term survival rate has stagnated in the past decades. Previous studies have shown that tumors in the G2/M phase are more sensitive to radiotherapy. The proto-oncogene c-myc is a transformed member o...

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Detalles Bibliográficos
Autores principales: Fan, Yunpeng, Jia, Xiaofeng, Xie, Tao, Zhu, Liulong, He, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640369/
https://www.ncbi.nlm.nih.gov/pubmed/33125136
http://dx.doi.org/10.3892/or.2020.7806