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Effect of age and sex on immune checkpoint expression and kinetics in human T cells

BACKGROUND: Immune checkpoints are crucial molecules in maintaining a proper immune balance. Even though age and sex are known to have effects on the immune system, the interplay between age, sex and immune checkpoint expression by T cells is not known. The aim of this study was to determine whether...

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Detalles Bibliográficos
Autores principales: Reitsema, Rosanne D., Hid Cadena, Rebeca, Nijhof, Sander H., Abdulahad, Wayel H., Huitema, Minke G., Paap, Davy, Brouwer, Elisabeth, Boots, Annemieke M. H., Heeringa, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640492/
https://www.ncbi.nlm.nih.gov/pubmed/33292359
http://dx.doi.org/10.1186/s12979-020-00203-y