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Differential responses in placenta and fetal thymus at 12 days post infection elucidate mechanisms of viral level and fetal compromise following PRRSV2 infection

BACKGROUND: A pregnant gilt infected with porcine reproductive and respiratory syndrome virus (PRRSV) can transmit the virus to her fetuses across the maternal-fetal-interface resulting in varying disease outcomes. However, the mechanisms leading to variation in fetal outcome in response to PRRSV in...

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Detalles Bibliográficos
Autores principales: Van Goor, Angelica, Pasternak, Alex, Walker, Kristen, Hong, Linjun, Malgarin, Carolina, MacPhee, Daniel J., Harding, John C. S., Lunney, Joan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640517/
https://www.ncbi.nlm.nih.gov/pubmed/33148169
http://dx.doi.org/10.1186/s12864-020-07154-0