Generation of isogenic Propionyl-CoA carboxylase beta subunit (PCCB) deficient induced pluripotent stem cell lines

Propionic acidemia (PA) is an autosomal recessive metabolic liver disease caused by defects in propionyl CoA carboxylase. Propionyl CoA carboxylase is a dodecameric enzyme consisting of multiple copies of alpha and beta subunits encoded by the PCCA and PCCB genes. Mutations in either PCCA or PCCB ca...

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Detalles Bibliográficos
Autores principales: Pournasr, Behshad, Duncan, Stephen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640943/
https://www.ncbi.nlm.nih.gov/pubmed/32822967
http://dx.doi.org/10.1016/j.scr.2020.101953

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640943/
https://www.ncbi.nlm.nih.gov/pubmed/32822967
http://dx.doi.org/10.1016/j.scr.2020.101953

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