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Generation of isogenic Propionyl-CoA carboxylase beta subunit (PCCB) deficient induced pluripotent stem cell lines
Propionic acidemia (PA) is an autosomal recessive metabolic liver disease caused by defects in propionyl CoA carboxylase. Propionyl CoA carboxylase is a dodecameric enzyme consisting of multiple copies of alpha and beta subunits encoded by the PCCA and PCCB genes. Mutations in either PCCA or PCCB ca...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640943/ https://www.ncbi.nlm.nih.gov/pubmed/32822967 http://dx.doi.org/10.1016/j.scr.2020.101953 |