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Desacetyl-α-MSH and α-MSH have sex specific interactions with diet to influence mouse gut morphology, metabolites and microbiota
The melanocortin peptides have an important role in regulating body weight and appetite. Mice that lack the desacetyl-α-MSH and α-MSH peptides (Pomc(tm1/tm1)) develop obesity. This effect is exacerbated by a high fat diet (HFD). However, development of obesity in female Pomc(tm1/tm1) mice during chr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641164/ https://www.ncbi.nlm.nih.gov/pubmed/33144604 http://dx.doi.org/10.1038/s41598-020-75786-z |