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ArfB can displace mRNA to rescue stalled ribosomes

Ribosomes stalled during translation must be rescued to replenish the pool of translation-competent ribosomal subunits. Bacterial alternative rescue factor B (ArfB) releases nascent peptides from ribosomes stalled on mRNAs truncated at the A site, allowing ribosome recycling. Prior structural work r...

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Detalles Bibliográficos
Autores principales: Carbone, Christine E., Demo, Gabriel, Madireddy, Rohini, Svidritskiy, Egor, Korostelev, Andrei A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641280/
https://www.ncbi.nlm.nih.gov/pubmed/33144582
http://dx.doi.org/10.1038/s41467-020-19370-z