Cargando…

ArfB can displace mRNA to rescue stalled ribosomes

Ribosomes stalled during translation must be rescued to replenish the pool of translation-competent ribosomal subunits. Bacterial alternative rescue factor B (ArfB) releases nascent peptides from ribosomes stalled on mRNAs truncated at the A site, allowing ribosome recycling. Prior structural work r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carbone, Christine E., Demo, Gabriel, Madireddy, Rohini, Svidritskiy, Egor, Korostelev, Andrei A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641280/ https://www.ncbi.nlm.nih.gov/pubmed/33144582 http://dx.doi.org/10.1038/s41467-020-19370-z

Ejemplares similares

Mechanism of ribosome rescue by ArfA and RF2
por: Demo, Gabriel, et al.
Publicado: (2017)

Extensive ribosome and RF2 rearrangements during translation termination
por: Svidritskiy, Egor, et al.
Publicado: (2019)

Structural basis for +1 ribosomal frameshifting during EF-G-catalyzed translocation
por: Demo, Gabriel, et al.
Publicado: (2021)

Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM
por: Loveland, Anna B., et al.
Publicado: (2022)

Alkylative damage of mRNA leads to ribosome stalling and rescue by trans translation in bacteria
por: Thomas, Erica N, et al.
Publicado: (2020)

Cryo-EM of elongating ribosome with EF-Tu•GTP elucidates tRNA proofreading
por: Loveland, Anna B., et al.
Publicado: (2020)

The fail-safe system to rescue the stalled ribosomes in Escherichia coli
por: Abo, Tatsuhiko, et al.
Publicado: (2014)

Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine
por: Koh, Cha San, et al.
Publicado: (2017)

Time-resolved cryo-EM visualizes ribosomal translocation with EF-G and GTP
por: Carbone, Christine E., et al.
Publicado: (2021)

Ribosome•RelA structures reveal the mechanism of stringent response activation
por: Loveland, Anna B, et al.
Publicado: (2016)

ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue
por: Kurita, Daisuke, et al.
Publicado: (2014)

Sequential rescue and repair of stalled and damaged ribosome by bacterial PrfH and RtcB
por: Tian, Yannan, et al.
Publicado: (2022)

Identification of residues required for stalled-ribosome rescue in the codon-independent release factor YaeJ
por: Kogure, Hiroyuki, et al.
Publicado: (2014)

mRNA stem-loops can pause the ribosome by hindering A-site tRNA binding
por: Bao, Chen, et al.
Publicado: (2020)

Structure of RNA polymerase bound to ribosomal 30S subunit
por: Demo, Gabriel, et al.
Publicado: (2017)

An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation
por: Toribio, René, et al.
Publicado: (2016)

The Expression of Antibiotic Resistance Methyltransferase Correlates with mRNA Stability Independently of Ribosome Stalling
por: Dzyubak, Ekaterina, et al.
Publicado: (2016)

Ribosomal stalling landscapes revealed by high-throughput inverse toeprinting of mRNA libraries
por: Seip, Britta, et al.
Publicado: (2018)

Ubiquitination of stalled ribosome triggers ribosome-associated quality control
por: Matsuo, Yoshitaka, et al.
Publicado: (2017)

A stalled-ribosome rescue factor Pth3 is required for mitochondrial translation against antibiotics in Saccharomyces cerevisiae
por: Hoshino, Soichiro, et al.
Publicado: (2021)

SMG-6 mRNA cleavage stalls ribosomes near premature stop codons in vivo
por: Kim, John H, et al.
Publicado: (2022)

B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage
por: Park, Esther, et al.
Publicado: (2023)

Ubiquitination of stalled ribosomes enables mRNA decay via HBS-1 and NONU-1 in vivo
por: Monem, Parissa C., et al.
Publicado: (2023)

Ribosome-associated Asc1/RACK1 is required for endonucleolytic cleavage induced by stalled ribosome at the 3′ end of nonstop mRNA
por: Ikeuchi, Ken, et al.
Publicado: (2016)

Human NMD ensues independently of stable ribosome stalling
por: Karousis, Evangelos D., et al.
Publicado: (2020)

The deubiquitylase USP9X controls ribosomal stalling
por: Clancy, Anne, et al.
Publicado: (2021)

In vitro Analysis of Stalled Ribosomes Using Puromycin Incorporation
por: Scarpitti, MaKenzie R., et al.
Publicado: (2023)

The ribosome quality control pathway can access nascent polypeptides stalled at the Sec61 translocon
por: von der Malsburg, Karina, et al.
Publicado: (2015)

YaeJ is a novel ribosome-associated protein in Escherichia coli that can hydrolyze peptidyl–tRNA on stalled ribosomes
por: Handa, Yoshihiro, et al.
Publicado: (2011)

Ensemble cryo-EM elucidates the mechanism of translation fidelity
por: Loveland, Anna B., et al.
Publicado: (2017)

Mechanisms of ribosome stalling by SecM at multiple elongation steps
por: Zhang, Jun, et al.
Publicado: (2015)

The Ribosome Restrains Molten Globule Formation in Stalled Nascent Flavodoxin
por: Houwman, Joseline A., et al.
Publicado: (2016)

Identifying Small Proteins by Ribosome Profiling with Stalled Initiation Complexes
por: Weaver, Jeremy, et al.
Publicado: (2019)

Toxin-mediated ribosome stalling reprograms the Mycobacterium tuberculosis proteome
por: Barth, Valdir C., et al.
Publicado: (2019)

CAT tails drive degradation of stalled polypeptides on and off the ribosome
por: Sitron, Cole S., et al.
Publicado: (2019)

Correction: The deubiquitylase USP9X controls ribosomal stalling
por: Clancy, Anne, et al.
Publicado: (2021)

Structure of Gcn1 bound to stalled and colliding 80S ribosomes
por: Pochopien, Agnieszka A., et al.
Publicado: (2021)

Translational buffering by ribosome stalling in upstream open reading frames
por: Bottorff, Ty A., et al.
Publicado: (2022)

Ribosome Stalling of N-Linked Glycoproteins in Cell-Free Extracts
por: Chung, Sean S., et al.
Publicado: (2022)

Identification of factors that prevent ribosome stalling during early elongation
por: Hye-Rim, Hong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_l25cbpud4n843um56jqurhbgkn