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Improving the prediction accuracy of protein abundance in Escherichia coli using mRNA accessibility

RNA secondary structure around translation initiation sites strongly affects the abundance of expressed proteins in Escherichia coli. However, detailed secondary structural features governing protein abundance remain elusive. Recent advances in high-throughput DNA synthesis and experimental systems...

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Detalles Bibliográficos
Autores principales: Terai, Goro, Asai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641306/
https://www.ncbi.nlm.nih.gov/pubmed/32504488
http://dx.doi.org/10.1093/nar/gkaa481