qDRIP: a method to quantitatively assess RNA–DNA hybrid formation genome-wide

R-loops are dynamic, co-transcriptional nucleic acid structures that facilitate physiological processes but can also cause DNA damage in certain contexts. Perturbations of transcription or R-loop resolution are expected to change their genomic distribution. Next-generation sequencing approaches to m...

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Detalles Bibliográficos
Autores principales: Crossley, Magdalena P, Bocek, Michael J, Hamperl, Stephan, Swigut, Tomek, Cimprich, Karlene A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641308/
https://www.ncbi.nlm.nih.gov/pubmed/32544226
http://dx.doi.org/10.1093/nar/gkaa500

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641308/
https://www.ncbi.nlm.nih.gov/pubmed/32544226
http://dx.doi.org/10.1093/nar/gkaa500

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