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qDRIP: a method to quantitatively assess RNA–DNA hybrid formation genome-wide
R-loops are dynamic, co-transcriptional nucleic acid structures that facilitate physiological processes but can also cause DNA damage in certain contexts. Perturbations of transcription or R-loop resolution are expected to change their genomic distribution. Next-generation sequencing approaches to m...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7641308/ https://www.ncbi.nlm.nih.gov/pubmed/32544226 http://dx.doi.org/10.1093/nar/gkaa500 |